The recently described clinical spectrum for FAD synthase deficiency has ranged from neonatal-onset, a lethal disease with metabolic myopathy, cardiomyopathy, swallowing, speech difficulties, and respiratory insufficiency, to later-onset, a potentially treatable neuromuscular disorder with lipid storage myopathy, MADD-like metabolic aberrations, and combined respiratory-chain deficiency [34]
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T-2 toxin can induce apoptosis in many types of cells bearing rapid rates of proliferation [103] and increased the expression of both oxidative stress and apoptosis related genes in hepatocytes of mice [104]
As you can imagine, the frequency of injections drops way down
After four hours, we should observe a drop in TMA concentration within the solution and an increase in TMAO