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Some people on GLP-1 medications do experience more serious side effects like bowel obstruction, gallstone attacks, or gastroparesis (a condition where your stomach muscles dont move food in the way they should)

Both Mounjaro and Zepbound injector pens and Zepbound single-dose vials don't contain preservatives and are approved for single-use only, so dose-splitting or microdosing is not contemplated by the FDA-label, the company notes

95% CI, 1.041.43) compared with controls [65]

Compounding also allows dosing flexibility, which supports gradual titration and longer-term use

GLP-2 suppresses LPS-induced inflammation in macrophages by inhibiting ERK phosphorylation and NF-kappaB activation

Mol Cell Endocrinol