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Met can abrogate not only the decrease in testis weight but also the reduction in the number of spermatogonia, Sertoli cells, and Leydig cells []

Cystathionine -synthase overexpression drives metastatic dissemination in pancreatic ductal adenocarcinoma via inducing epithelial-to-mesenchymal transformation of cancer cells

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However, GR also is involved in increasing blood glucose (Undesirable in diabetic patients), meaning this needs to be offset by corresponding decreases in blood glucose via GLP1R