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Keywords: glucagon-like peptide-1 receptor agonists, ocular diseases, glaucoma, diabetic retinopathy, mechanism 1 Introduction Glucagon-like peptide-1 (GLP-1) is an incretin hormone released from gut enteroendocrine cells and regulates blood sugar by increasing insulin while reducing glucagon secretion and inhibiting stomach emptying and food intake (Drucker, 2022)

First week: Mild nausea, fatigue, or headaches are most common Weeks 24: Symptoms often lessen as the body adapts After one month: Many people report minimal or no ongoing side effects Side effects may briefly return after dose increases, then improve again

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Orforglipron vs Farxiga: A New Chapter in Oral Diabetes Therapy Big news from the diabetes frontEli Lillys oral GLP-1 candidate Orforglipron just outperformed Farxiga (dapagliflozin) in two Phase III trials

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