Emerging reports have flagged rare visual disturbances , including non-arteritic anterior ischaemic optic neuropathy (NAION) in some users of GLP-1 agonists
Tesamorelin pairs effectively with tissue repair peptides
The formation of ice crystals can physically damage the peptide structures
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Strength of recommendation: 1B Rationale: Atrial fibrillation is the most common arrhythmia worldwide and substantially increases the risk of stroke and thromboembolic events.130 Both DM and CKD are associated with an increased risk of developing atrial fibrillation as compared to the general population.130132 Furthermore, the presence of DM and/or CKD in patients with atrial fibrillation increases the risk of thromboembolic events,133136 as well as mortality and bleeding risks.136,137 The most common score used to estimate the thromboembolic risk and indication for oral anticoagulation is the CHA2DS2-VASc,130 and DM is one of the score items, therefore most patients with diabetes and CKD will indicate oral anticoagulation