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Moreover, an open, single-arm, first-in-human trial of PU-H71 in patients with advanced solid tumors showed that the incidence of grade 2 adverse events such as common nausea, headache, and fatigue was extremely low, and only one patient exhibited a grade 3 adverse event (vomiting) that could be related to PU-H71

Devarajan TV, Venkataraman S, Kandasamy N, et al

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2 Department of Endocrinology, First Hospital of Shanxi Medical University, Shanxi Medical University, Taiyuan, 030001, Peoples Republic of China *These authors contributed equally to this work Correspondence: Yi Zhang

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