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Metabolic changes associated with the clusters suggest that altered regulation of cellular metabolism, especially of mitochondrial bioenergetics, were common metabolic phenotypes in this cohort of autistic participants

Finally, enzymes not belonging to either group are categorized as other enzymes. We separated enzymes into these three classes for each dataset and virus using flux balance analysis (see Methods)

Abscisic acid homeostasis is mediated by feedback regulation of MdMYB88 and MdMYB124

Clinical improvements are typically observed within 812 weeks, with optimal results seen over 36 months depending on severity and compliance