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BMC Cancer 16 , 105 (2016)

Moreover, defensins are agonists for cytokine or chemokine receptors and represent a link between the innate and adaptive immunity [135137]

This approach not only augments therapeutic effectiveness but also alleviates the risk of resistance linked to monotherapies

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[7] Another report showed pre-treatment with 85 mg (approximately 4000 mg/kg) alpha-tocopherol reduced the lethality of a single 15 mg/kg dose of doxorubicin from 85 percent to 10 percent in mice

doi: 10.2337/DB14-1497 63 PuglieseAZellerMFernandezAZalcbergLJBartlettRJRicordiCet al