Its unknown if this risk applies to humans, but: Do not use if you have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)
What's the optimal dosing
However, native GLP-1 has a limited half-life (1.55 min) due to its degradation by the enzyme Dipeptidyl peptidase 4 (DPP-4), necessitating the development of GLP-1 receptor agonists (GLP-1RAs) with longer activity (Campbell and Drucker 2013)
Geraets AFJ, Khler S, Muzambi R, Schalkwijk CG, Oenema A, Eussen SJPM, et al
Your path to enhanced vitality won't be based on guesswork or generic solutions
For gut hormones, almost significant differences in basal levels of PYY and GLP-1 were found in the PLC group comparing subjects that improved and not improved HbA1c