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Using tissue from donors, the team observed that cells in the nucleus pulposus, a jelly-like structure at the center of intervertebral discs, had a lower amount of this peptide receptor when degeneration increased

Estas modificaciones incluyen la sustitucin de alanina por cido aminoisobutrico (Aib) en la posicin 8, la sustitucin de lisina por arginina en la posicin 34, y la acilacin en la posicin 26 con un cido graso C18 mediante un espaciador

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doi:10.1038/clpt.2010.184 Lyssenko V, Lupi R, Marchetti P et al (2007) Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

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Chromatin-modifying agents in anti-cancer therapy