clinical trials for semaglutide show impressive weight-loss results with GLP-1RA therapies — but do those results hold up in real life? GLP-1RA-based weight-loss therapies, including liraglutide, semaglutide, and tirzepatide, may perform differently in real-world New Wegovy clinical trial finds

The main limitations of this study were its small size and short duration, as well as its open-label design

When the study group was stratified by BMI, adults without obesity, those with class I obesity (BMI: 30-34.99 kg/m2) and those with class II obesity (BMI: 35-39.99 kg/m2) were less likely to have all-cause hospital admissions, ED visits, undergo an endoscopic procedure, receive a prescription for a prokinetic, and receive a laxative prescription if they used an incretin-based drug compared with nonusers

Racking up tens of billions of dollars in sales, their ripple is already being felt across supermarket aisles, restaurants, fashion chains, gyms, airlines, and more, redefining how people spend their money and forcing businesses to adapt to a new normal

& Farquhar, C

While you can get vitamin C from citrus and peppers, and sulfur-rich foods support glutathione production, modern lifestyles and environmental stressors often increase the bodys demand for these nutrients

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