Importantly, this transcriptomic analysis demonstrated that 6 genes significantly altered in metformin-treated SW837 cells are complex I genes, a known target of metformin treatment, further supporting oxidative phosphorylation as a metabolic target of metformin treatment in rectal cancer
Gastroenterology 109:19071916 Schmidt LE (2005) Age and paracetamol self-poisoning
Source : Brakedal et al., Cell Metabolism (2022)
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Additionally, ascorbate, DHA, and glucose are all internalized by GLUT1
