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The primary cause is the musculoskeletal adjustment to changing body weight, though inflammation from dehydration and nutrient deficiencies can amplify the sensation

doi: 10.1038/s41586-021-03218-7 155 KayagakiN.StoweI

bright lights, loud noises, strong scents, and cold) Dimension 3 - Common medical comorbidities: Somatic pain disorders Psychiatric conditions Sleep disorders Somatic diseases Dimension 4 - Neurobiological, psychological, and functions consequences: Poor quality of life High costs that indirectly stem from the burden of fibromyalgia Dimension 5 - Putative neurobiological and psychosocial mechanisms, risk factors, and protective factors: Familitary for functional pain disorders Environmental stressors that may trigger fibromyalgia: Early lifetime adverse events Trauma Medical conditions Psychosocial stressors Central sensitization - A Deeper Level Central sensitization can be defined as a state in which the central nervous system amplifies sensory input and creates an enhanced response to sensation (AKA wind-up)

Long-Term Wellness : The effects of Ipamorelin can lead to long-term improvements in health and wellness, rather than just temporary relief