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However, most existing reviews primarily focus on their discovery, structural features, classification, functional diversity, and regulatory mechanisms under specific stress conditions

The key question driving next-generation design is whether adding the glucagon receptor (GcgR) to dual GLP-1/GIP agonists can unlock additional efficacy

These multifaceted metabolic effects position dual GLP-1/GIP receptor agonists as superior therapeutic candidates for MASLD, especially in patients with coexisting obesity and T2DM, where dysregulated glucose and lipid metabolism drive the progression of the disease

For children, it's important to consult a doctor before starting any supplement regimen

AC also ameliorated diabetic kidney disease by regulating the phosphatidylinositol 3-kinase (PI3K)/AKT/NF-B signaling pathway and alleviating pyroptosis (Zhang et al