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The mechanisms of action are fundamentally different: GLP-1 agonists are synthetic or modified peptides designed to mimic incretin hormones and directly stimulate specific cellular receptors, while allulose is a simple sugar that undergoes passive absorption and excretion

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30 In the LEAD 6 trial, following the main 26week, randomised, doubleblind phase, 187 patients who had been receiving exenatide twice daily 10 g were switched to liraglutide 1.8 mg

Avoid use during pregnancy or breastfeeding

Having said that, compounded semaglutide can be a helpful option during Ozempic and Wegovy shortages , as well as for people who cannot take Ozempic and Wegovy in their standard form

After the first injection, tirzepatide levels gradually increase over several weeks