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It is evidence-based injury management that applies whether BPC-157 is being used or not, and it applies more urgently precisely because BPC-157 removes the pain signal that would otherwise enforce appropriate rest

Altered B12 handling and reduced clearance in kidney disease, and both cellular release and reduced clearance in liver disease, can raise B12, so supportive renal or hepatic findings make those causes plausible

Tirzepatide, which acts on both GIP and GLP-1 receptors, appears to have a somewhat more favorable GI tolerability profile, possibly because GIP receptor activation partially counteracts the nausea-inducing effects of GLP-1 agonism