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White tomato extract helps protect skin from UV-related stress and promote a brighter tone, while collagen and elastin improve elasticity and firmness

Other biological processes, such as persistent viral reservoirs, chronic inflammation, autoimmunity, dysbiosis and microthrombotic phenomena, are also likely to contribute to the complex clinical manifestations of the syndrome

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Cell Metab (2018) 27:616629.e614

Due to distinct tissue expression of receptors, MT-2 is incorporated alongside selective antagonists, genetic models, or specific interventions to attribute observed effects to receptor subtypes