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Mimics natural amylin released by the pancreas, signaling satiety to the area postrema and other brainstem regions involved in appetite control

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This cytokine storm promotes a self-sustained inflammatory reaction which, contributing to the destruction of the endothelium, leads to acute respiratory distress syndrome, multiple organ failure, and death

ManiBKWalkerAKLopez SotoEJRaingoJLeeCEPerellMet al

There are also earlier time-point observations in the literature