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Dl-3- n -butylphthalide enhances collateral circulation by promoting endothelial nitric oxide synthase activity and activates neurotrophic signaling pathways such as brain-derived neurotrophic factor/tropomyosin receptor kinase B (TrkB) and calcitonin gene-related peptide (CGRP), thereby improving synaptic plasticity and cognitive recovery 17 (Fig
[63] [72] The development of a genetically-regulated trait or disorder that is dependent on the inheritance of two or more genes is termed oligogenic inheritance or polygenic inheritance
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Massart R, Mongeau R, Lanfumey L
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