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thus, the accumulation of misfolded proteins, dysfunctional organelles, or irreversible aggregates has disproportionately severe consequences

Environmental exposure matters

Zinkov refused to accept what the medical establishment deemed normal. Frustrated by a system that often overlooks the unique challenges women face such as brain fog, fatigue, weight gain, and metabolic dysfunction she embarked on a mission to change the narrative

In the nigrostriatal tract system, dopamine undergoes autooxidation or oxidative deamination by monoamine oxidase-B, both of which aggravates with age, leading to increased production of peroxides and hydroxyl radicals 41