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in 2008, the dysregulation of NRF-2 is necessary in the development of type 2 diabetes and its complications [95]

J Appl Physiol 98(4):11541162

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Animal data from rodent models show that pharmacological GHSR-1a stimulation during peripubertal windows alters adult hypothalamic gene expression, though whether this finding translates to humans remains untested [6]