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Autoimmune disorders: In some cases, the bodys immune system can attack the cells that produce intrinsic factors, leading to pernicious anemia

There is no established safety data for the combination in any population, so the honest position is that contraindication data does not exist at the combination level

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Intramuscular injections may be preferred for deeper absorption , while subcutaneous options may offer ease of use in at-home settings when clinically appropriate

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