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Additionally, certain bioactive compounds induce CYP enzyme activity, accelerating drug metabolism and reducing therapeutic efficacy

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Cagrilintide offers a focused, amylin-based strategy with milder side effects and strong combination therapy potential

NAC limits the hepatoxicity of APAP by increasing the synthesis of GSH in the liver [39]

229 Indeed, it has been shown that nicotinic acid can rescue the inhibitory activity of NAMPT inhibitors in those cancer models that express NAPRT