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Beatty, S., Koh, H., Phil, M., Henson, D

Nie, Gut hormones in microbiota-gut-brain cross-talk

BCAAs in disease Metabolic disease Existing studies point out that BCAAs and their metabolites are the strongest biomarkers of metabolic diseases such as obesity, insulin resistance, and type 2 diabetes (T2D)

Long-term exposure to these medications can exacerbate obesity and related cardiometabolic complications, which in turn may worsen depressive outcomes and reduce treatment adherence [98,99,100]

It adds that manufacturers routinely file additional patents covering new formulations, delivery systems, or uses, which prolongs exclusivity well past the original expiry date

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