GLP-1 medications, originally used for those with Type 2 diabetes, have recently grown in popularity as a weight management tool with brand name drugs such as Ozempic, WeGovy and Byetta
The result is a medication that helps people consume less and burn more energy while also balancing blood sugar and supporting breakdown of fat, which is why it has shown greater weight loss in early studies, says Rhodes
Severe, persistent or worsening side effects should not be ignored
As well, metformin has a profound effect on the alleviation of dopaminergic neurodegeneration in the SN and associated neuroinflammation (Shukla et al
However, these results come from different trial stages and designs, making a direct comparison difficult
Drug Design, Development and Therapy , 9, 2485 2499