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Early studies demonstrated that Ipamorelin effectively activated the growth hormone secretagogue receptor (GHS-R1a), resulting in increased growth hormone secretion through ghrelin-related signaling mechanisms

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Regarding lactation, there are no data on tirzepatide presence in human milk, effects on the breastfed infant, or effects on milk production

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Liraglutide exposure was associated with early embryonic deaths and an imbalance in some fetal abnormalities in pregnant rats administered liraglutide during organogenesis at doses that approximate clinical exposures at the maximum recommended human dose (MRHD) of 3 mg/day