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Furthermore, they found that targeted elimination of senescent cells while sparing healthy tubular cells can be achieved through low-dose administration of the ferroptosis inducer RSL3 [167]

Intracellularly, NBT (or DCFH-DA probe) interacts with superoxide, which produces water-insoluble and stable formazan crystals (formazan precipitates after reacting) that can be detected by microscopy for the in situ localization of oxidants, for instance in the sperm pellet

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Common nonclinical applications include analytical reference work, peptide stability studies, and biochemical assay development in controlled lab settings

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