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It is because high GSSG in a cell makes it prone to damage

Transient ectopic expression of MrGST1 in combination with MrMYB1.1 and MrbHLH1 dramatically boosted pigmentation in Nicotiana tabacum leaves in contrast to MrMYB1.1 and MrbHLH1

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In senescent cells, FOXO4 can help retain p53 in the nucleus, which supports a senescent survival state