It separately notes that nausea and reduced intake can lower sodium and potassium, while creatine further concentrates urine
Count to 3 after injecting to allow medication to fully dispense into the tissue
Gastrointestinal side effects are by far the most prevalent during early treatment: Nausea Very common (may affect more than 1 in 10 people), typically peaking during the first week and often improving over two to four weeks [1] [2] Vomiting Common (may affect up to 1 in 10 people), usually occurring alongside nausea [1] [2] Diarrhoea Common, may persist for several weeks Constipation Common, sometimes alternating with diarrhoea Abdominal pain or discomfort Common, ranging from mild cramping to more pronounced discomfort Dyspepsia (indigestion) Common Eructation (belching) Common Reduced appetite A therapeutic effect that may feel uncomfortable initially, affecting eating patterns These symptoms arise because semaglutide mimics the natural GLP-1 hormone, which slows gastric emptying and increases satiety

I felt less hungry than usual, but not exactly full, and it was not difficult for me to eat (even if I abandoned my lunch of salad and pita roughly halfway through, as I started to feel slightly nauseated)
Kidney disease and renoprotection
Digestive Enzymes and Ozempic: Safety, Interactions and Management Digestive enzymes and Ozempic are increasingly discussed together as more people experience gastrointestinal symptoms whilst taking semaglutide for type 2 diabetes