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What I definitely dont recommend is getting sidetracked by those patches or other alternatives that arent actually proven to work

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Discussion FSEC-TS assays for fluorescently tagged membrane proteins are best performed at temperatures where the tags are largely unaffected (~25% drop of fluorescence) so that the decrease of fluorescence can be largely attributed to the aggregation/precipitation of protein of interest (POI)

Because GHK-Cu is frequently tucked inside a "proprietary blend," most labels don't let you know