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Senescent cells stop producing collagen, begin secreting enzymes that degrade existing collagen and elastin, and create a local inflammatory environment that accelerates surrounding tissue aging

The simultaneous activation of GIP and GLP-1 receptors may have central synergistic effects on appetite control, greater than selective GLP-1 receptor agonists [55], although preliminary studies do not support this hypothesis [56]

The second is the evidence gap : because the blend has never been trialed as a fixed product, every dose, schedule and timeline here is inference from the two component literatures, not a proven blend outcome

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