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Back Jin, T (May 2023) 'Tirzepatide, a new class of incretin-based drug for diabetes' , Obesity Medicine , 39, 1000483

In both liver and fat tissues, these effects were linked to the downregulation of FAS and SREBP-1, the upregulation of PPAR, and the stimulation of AMPK (AMP-activated protein kinase signaling)

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Specifically, the reduction of calories with or without fasting resulted in sex specific reduction of A plaques in both cortex and hippocampus

Lee JK, Shin JH, Gwag BJ, Choi E-J (2015) Iron accumulation promotes TACE-mediated TNF- secretion and neurodegeneration in a mouse model of ALS