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The cardiovascular safety demonstrated by tirzepatide in this analysis and SURPASS-4 paved the way for a large-scale cardiovascular outcomes trial

(2022) suggested a rise of the total bilirubin level in the plasma, perhaps due to GLP-induced hemolysis

Similarly, the natural flavonoid 4,5,7-trihydroxyflavone boosts the neurotrophic effects of BDNF by strengthening TrkB receptor signaling (Zhang et al., 2015