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J Neurosci (2020) 40(48):932741

Furthermore, GPER activation not only improves insulin sensitivity by suppressing hepatic inflammatory responses but also further reduces hepatic fat accumulation [10]

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Biomarker and Genetic Considerations for Personalized Choice Genetic variants in GLP1R and GIPR influence how effectively these medications engage their target receptors

It has also been approved for use in liver and kidney damage, with no requirement of dose adjustment [32, 82]

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