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The goal of GLP-1 care is less visceral and liver fat while preserving muscle, not uncontrolled under-eating

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Ideally, this should be spread throughout the day to ensure protein intake at each meal and snack

(When I asked ChatGPT to find compounding pharmacies that provide GLP-1 agonists, it could not produce any.) That means most patients will have to rely on autopen devices, which provide higher doses than typically used in ME/CFS, or vials

Some patients may ask about switching from semaglutide to tirzepatide if weight loss slows, side effects become difficult, blood sugar goals change, or they are not seeing the desired response

The triple-agonist mechanism of retatrutide engages three distinct metabolic pathways