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The current level considered sufficient for folate in plasma (i.e

de Almeida AJPO, de Oliveira JCPL, da Silva Pontes LV, de Souza Jnior JF, Gonalves TAF, Dantas SH, et al

Bonham MJ, et al

7 In patients with T2DM, the release of incretin hormones is physiologically insufficient, thereby compromising the ability to adequately secrete insulin and also execute other physiologic processes required to meet the metabolic requirements to maintain normoglycemia

In parallel, the landscape of pharmacological therapies for T2DM and (to a lesser extent) obesity has expanded in recent decades with new classes of molecules coming into the market

We set realistic expectations based on evidence