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Unfortunately, despite the vast amounts of GSH needed to be transported into and out of organelles and cells, knowledge of transporter proteins in humans is still not complete [67]

10.1038/nm.4194 411 SteinM

IV delivery maximizes effectiveness : Intravenous administration achieves 100% bioavailability compared to oral supplements' 2-10% absorption rate for both compounds

The therapeutic dose for wound healing in pigs (1.1 mg/kg) is approximately 300 times below the toxic threshold

Singh, Evaluation of oxidative stress before and after control of glycemia and after vitamin E supplementation in diabetic patients, Metabolism