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GLP-1 is mainly produced in the enteroendocrine L cells located in the distal intestine exerting its effects through binding to the GLP-1 receptors (GLP-1R) expressed in the pancreas, heart, blood vessels, gastrointestinal tract (GIT), kidney, lung, breast, and central nervous system [11],[12]

U., Ozerova, I

Randomized clinical trial of dialysate cooling and effects on brain white matter

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Clinical trials generally identify the most dangerous side effects of drugs, adds co-author Ungar

By activating AMPK, metformin promotes the nuclear translocation and transcriptional activity of FOXO3 and then inhibits the proliferation, self-renewal, and invasion ability of glioma stem cells