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Open questions include tissue-selective delivery, chronic dosing effects on one-carbon metabolism, and interactions with NAD precursor strategies [14,8,9]

B12 Injections are safe and effective for most people

Do I need blood tests before a vitamin B12 injection

However, in patients treated with diclofenac and glucocorticoids, the risk of peptic ulcer and gastrointestinal bleeding may increase, so special attention should be given in case of prolonged treatment, even in the absence of serious gastrointestinal symptoms

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