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Chemoresistance towards EGFR inhibition by small molecule tyrosine kinase inhibitors such as gefitinib or erlotinib are common features in clinical trials

Sikiric P., Hahm K.B., Blagaic A.B., et al

Cyanocobalamin is the most widely used form of vitamin B 12, and has hematopoietic activity apparently identical to that of the antianemia factor in purified liver extract

They present antigens, modulate T cell activation, and skew immune polarization toward Th17 and Th2 dominance, patterns commonly observed in autoimmune conditions

Educated guesses, not evidence-based medicine

Researchers are also exploring its potential in addressing chronic conditions, such as inflammatory disorders and degenerative diseases