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Topotecan, a new topoisomerase I (Topo I) inhibitor, has significant activity in patients with chronic myelomonocytic leukemia (CMML)

However, these disorders frequently affect not only the interstitium, but also the air spaces, peripheral airways, and blood vessels

The peptide is endogenously present in human plasma at low nanomolar concentrations in young adults, with the concentration declining with age (a finding from the original GHK research literature that is frequently cited in discussions of the compound)

Infolgedessen fhrt die Verwendung von menschlichem Wachstumshormon hufig zu einem Anstieg des Blutzuckerspiegels (als diabetogener Effekt bekannt)

Autophagy 11 , 729739 (2015)

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