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Our bodies rely on fat for energy when we do not eat for a stretch of time - like when we miss a meal or when we sleep The mutations result in missed or non-functional CACT (CACT deficiency).When the CACT normal enzyme is missing or not working well, the body cannot use fat for energy, and must rely solely on glucose Although glucose is a good source of energy, there is a limited amount available in the body

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Inflammopharmacology 25:439449 Novinscak T, Brcic L, Staresinic M, Jukic I, Radic B, Pevec D, Mise S, Tomasovic S, Brcic I, Banic T (2008) Gastric pentadecapeptide BPC 157 as an effective therapy for muscle crush injury in the rat