The 2019 Endocrine Society guideline also states: "We recommend against GH treatment for the purpose of athletic performance enhancement or anti-aging in otherwise healthy individuals" [19]
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NNMT competes for nicotinamide, pulling it out of the salvage pool toward methylation and excretion
Their functional enrichment analyses linked these genes to mRNA metabolic processes, immune cell regulation, and RNA transport pathways, confirming their potential role in OA pathogenesis and immune-mediated joint degradation (Huo et al., 2025)
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Faima Atta Khan, Fahad AlAsmari, and Muhammad Abdul Rahim conceptualized design of the work, data analysis, aided in drafting manuscript