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Dermatologists often refer to glutathione as the foundation antioxidant because when its replenished, other antioxidants like Vitamin C and E work more effectively too

Although iron levels do not increase during ferroptotic cell death, an increase in cellular iron could increase the vulnerability of cells to cell death

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Some mutations can lead to various neurological conditions, including neonatal mitochondrial encephalopathy, sensorineural hearing loss, axonal neuropathy, and, less commonly, motor neuron disease (9)

Zeng et al., 2024)

This may potentially be facilitated by the activation of adenylate cyclase, which might transform ATP to cAMP