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GLP-1 Receptor Agonists in Pediatric and Adolescent Obesity

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We review evidence suggesting that, collectively, these unresolved exogenous and endogenous cues drive liver injury, culminating in liver fibrosis and advanced sequelae of this disorder such as liver cirrhosis and hepatocellular carcinoma

Certain groups may be more vulnerable to the effects of muscle loss: Older adults Individuals with low baseline muscle mass People who are physically inactive Women in perimenopause or postmenopause In these populations, muscle loss can contribute to sarcopenia (age-related muscle decline) and increase the risk of falls, frailty and reduced independence