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Nowadays, FOXO4-DRI studies are focused on the following aspects: osteoarthritis (senescent chondrocyte clearance), metabolic dysfunction (insulin resistance and obesity-associated senescence), neurodegeneration (eliminating senescent brain cells), and fibrotic diseases (idiopathic pulmonary and liver fibrosis)

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10.3390/molecules22122145 166 ShengY.WuT.DaiY.XuL.ZhongY.XueY.et al (2020)