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Knockdown of GLS2 but not GLS1 can inhibit cysteine starvation-mediated ferroptosis of MEFs [86]

Summary The comparison between slu pp 332 and 5 amino 1mq shows two different approaches to metabolic research, each with its own advantages for scientific investigation

doi: 10.1080/09273948.2020.1740281 180 WuDLiuBYinJXuTZhaoSXuQet al

Consistently, they reduce DHA into ascorbate with a better efficiency ( k cat around 10 4 s 1 , k cat / K m around 10 7 M 1 .s 1 ) compared to the other enzymes ( k cat around 10 2 s 1 ) and to the reduction of glutathionylated-mercaptoethanol, the product formed upon incubation between GSH and HED ( k cat around 10 2 s 1 ) (Table 5) (Dixon et al., 2002)

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