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In scientific literature, NNMT is recognized as an enzyme that methylates nicotinamide (a precursor of NAD+) using S-adenosylmethionine (SAM) as the methyl donor, converting it to 1-methylnicotinamide (MNA) and potentially affecting cellular NAD+ availability

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Limit ambient-temperature handling time to help maintain compound integrity

In pregnant women, vitamin B12 deficiency can cause birth defects and developmental delays

Methylated vs synthetic forms Methylated B vitamins don't need the conversion steps that synthetic forms like cyanocobalamin require [25]

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