doi:10.1210/jcem.85.3.6439 [14] Homocysteine: Levels, tests, high homocysteine levels
But it's compelling enough to watch closely as trials progress
Six-eight week-old male C57BL/6J mice were administered a single injection with adeno-associated virus serotype 9 (AAV) via the tail vein to induce the heart-specific Pcsk5 overexpression under the transcriptional control of the CMV promoter (5 10 11 vg in 150 L per mouse) (AAV- Pcsk5 ) or the EC-specific Pcsk5 overexpression under the transcriptional control of the Icam2 promoter (1 10 12 vg in 150 L per mouse) (AAV-EC- Pcsk5 )
Check out Peters longevity chart You get into the bottom 50% of the quality of your life, in the last decade The average American lives to 80 or 81 If you dont smoke, are over 40, and arent suicidal, theres an 80% chance youll die of one of these four things: Cardiovascular and cerebrovascular disease Cancer Neurodegenerative disease Accidental deaths Peter recommends strength training, and to never stop strength training It can be the difference of breaking and not breaking your hip when youre 75 The 4 Dimensions of Health Span Cognition executive function, processing speed, short term memory Physical maintenance of muscle mass, functional movement, freedom from pain Sense of purpose and social support Capacity to cope with distress The Playbook for Living Longer The single most important thing you can do to live longer, is pick the right parents genetics can trump a lot The biggest leaps in human longevity came from sanitation developments, germ theory, and antibiotics Theres 7 things you can fiddle with food, exercise, sleep, modulation of stress, drugs, supplements, and hormones Triangulation putting together the insights for these three pillars: Looking at the data on centenarians (the people who live to be 100+), ~0.4% of people Examining non-humans (yeast, worms, flies, mice, apes etc.) experimenting and seeing how different things effect longevity Examining molecular insights with respect to longevity Example: certain cells in the body, senescents, are cells in the body programmed to do bad things
Food and Drug Administration and other cited public sources
If you're dealing with thinning hair or damaged nails, B12 injections can help give them the boost they need
