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Because BCAT is not present in hepatocytes, dietary BCAA, as well as gut microbiota-derived BCAA, pass through the liver and are deaminated by BCAT in other tissues, predominantly within skeletal muscle

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Efficacy and safety of co-administered once-weekly cagrilintide 24 mg with once-weekly semaglutide 24 mg in type 2 diabetes. Lancet 402(10403):720730

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